Name: La Quinta Inn & Suites by Wyndham Sioux Falls
Price range: $104 total
Rating: 9.2

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Your Eastern South Dakota Vacation

Locking in one of our vacation packages to Eastern South Dakota makes it a breeze to see and do more. Get set to experience this exciting destination's rural countryside and beyond. Your trip to Eastern South Dakota wouldn't be complete without getting to some of its best cities, starting with Sioux Falls. Some of the most popular attractions here include Denny Sanford Premier Center and Empire Mall. Mitchell is another favorite with Eastern South Dakota travelers. Visitors to this exciting destination enjoy Corn Palace and Mitchell Aquatic Center. Start packing your bags, because your Eastern South Dakota vacation is just a few clicks away with Expedia.

The Latest Eastern South Dakota vacation packages

Price found within the past 48 hours. Click for updated prices.

Microtel Inn & Suites by Wyndham Sioux Falls

Mall District

$408

per person

May 1 - May 4

found 1 day ago

Roundtrip non-stop flight included

Las Vegas (LAS) to Sioux Falls (FSD)

6.6/10 (1,002 reviews)

Room was ok, it was updated, but with that they most definitely got full size beds and are trying to pass them off as queen rooms and the headboard on the wall definitely show that. The options of doing their online check in is a waste with the man that checked me in because i had to do it all over again and he didn’t seem to understand the fact i had given all that was required already.

Reviewed on Jan 25, 2026

Bilmar Inn & Suites by Hotel O Hwy 77

$412

per person

Apr 17 - Apr 20

found 1 day ago

Roundtrip non-stop flight included

Philadelphia (PHL) to Sioux Falls (FSD)

7/10 Good! (303 reviews)

Clean and friendly also just off interstate

Reviewed on Dec 1, 2025

Best Western Plus Ramkota Hotel

Northwest Sioux Falls

$532

per person

May 1 - May 4

found 1 day ago

Roundtrip non-stop flight included

Las Vegas (LAS) to Sioux Falls (FSD)

8/10 Very Good! (1,002 reviews)

The room was really comfortable and the staff was excellent

Reviewed on Feb 6, 2026

Clubhouse Hotel Suites Sioux Falls

Mall District

$617

per person

May 1 - May 4

found 1 day ago

Roundtrip non-stop flight included

Las Vegas (LAS) to Sioux Falls (FSD)

9.6/10 Exceptional! (1,005 reviews)

Everything was perfect down to the comfy beds and pillows. Main complaint was the group of wrestlers. I feel they should have been in a separate area. Very noisy until 10pm then started at 5 am

Reviewed on Feb 27, 2026

AeroStay Hotel

North Sioux Falls

$502

per person

May 1 - May 4

found 1 day ago

Roundtrip non-stop flight included

Las Vegas (LAS) to Sioux Falls (FSD)

8.8/10 Excellent! (1,009 reviews)

Wonderful room! Great amenities- love that I can print for work here too!

Reviewed on Feb 25, 2026

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Where to stay in Eastern South Dakota

Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota

These falls are right in town surrounded by a nice park.

Downtown Sioux Falls

1 out of top 10 points of interest in this area

4.5/5(108 area reviews)

While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.

Discover the most popular places to visit in Eastern South Dakota

Beautiful park containing the famous Sioux Falls on the Sioux River in winter. What remains of a hundred year old mill can be seen. #waterfalls #siouxfalls #southdakota #travel #river #winter #ice #park #mill
#localgem #snow

Falls Park

Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.

Corn Palace

After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.

Fun zoo located in Sioux Falls, South Dakota. Highlights include: black rhinos, tigers, Giant tortoises, giraffes, cheetahs, alligators, bears, and camel rides.

Great Plains Zoo

Why not visit the native and exotic animals who live at Great Plains Zoo during your travels in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.

Eastern South Dakota Hotel Deals

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

1301 West Russell Sioux Falls SD

$64 nightly

$72 total

Mar 8 - Mar 9

Total with taxes and fees

7.8/10 Good! (1,520 reviews)

Good

Reviewed on Feb 27, 2026

Hotel On Phillips

100 N Phillips Ave Sioux Falls SD

Fully refundableReserve now, pay when you stay

$184 nightly

$204 total

Mar 5 - Mar 6

Total with taxes and fees

9.6/10 Exceptional! (1,353 reviews)

Beautiful place every time. Great location to fun.

Reviewed on Feb 27, 2026

La Quinta Inn & Suites by Wyndham Sioux Falls

4521 W. 41st Street Sioux Falls SD

Fully refundableReserve now, pay when you stay

$93 nightly

$104 total

Mar 8 - Mar 9

Total with taxes and fees

9.2/10 Wonderful! (1,550 reviews)

Clean room clean beds

Reviewed on Feb 27, 2026

See all 964 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.