Eastern South Dakota Vacation Packages 2026 from $449

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Your Eastern South Dakota Vacation

Locking in one of our vacation packages to Eastern South Dakota makes it a breeze to see and do more. Get set to experience this exciting destination's rural countryside and beyond. Your trip to Eastern South Dakota wouldn't be complete without getting to some of its best cities, starting with Sioux Falls. Some of the most popular attractions here include Denny Sanford Premier Center and Empire Mall. Mitchell is another favorite with Eastern South Dakota travelers. Visitors to this exciting destination enjoy Corn Palace and Mitchell Aquatic Center. Start packing your bags, because your Eastern South Dakota vacation is just a few clicks away with Expedia.

The Latest Eastern South Dakota vacation packages

Price found within the past 48 hours. Click for updated prices.

Bilmar Inn & Suites Dell Rapids Near Sioux Falls

$449

per person

Nov 5 - Nov 9

found 12 hours ago

Roundtrip flight included

Chicago (CHI) to Sioux Falls (FSD)

7/10 Good! (332 reviews)

Historic Twin Tudors Inn

$943

per person

Oct 1 - Oct 6

just found

Roundtrip flight included

Chicago (CHI) to Sioux Falls (FSD)

8.8/10 Excellent! (3 reviews)

We were upgraded to staying at the Victorian Inn- i would highly recommended. The house is charming and located in the historic downtown of Sioux Falls.

Reviewed on Jun 16, 2025

Microtel Inn & Suites by Wyndham Sioux Falls

Mall District

$538

per person

Oct 1 - Oct 6

found 1 day ago

Roundtrip flight included

Chicago (CHI) to Sioux Falls (FSD)

7.8/10 Good! (94 reviews)

La Quinta Inn & Suites by Wyndham Sioux Falls

Mall District

$555

per person

Nov 5 - Nov 9

found 12 hours ago

Roundtrip flight included

Chicago (CHI) to Sioux Falls (FSD)

9.2/10 Wonderful! (1,524 reviews)

Hard Rock Hotel & Casino Sioux City

$1,009

per person

Oct 1 - Oct 6

found 1 day ago

Roundtrip non-stop flight included

Baltimore (BWI) to Sioux City (SUX)

9.4/10 Exceptional! (1,000 reviews)

The food in the casino was not great at all. The casino has a lot of older slot machines, which is what we like. They also have a lot of newer slot machines too. The hotel itself is built into a very old building, so the layout is not what you would expect, but kind of cool.

Reviewed on Aug 28, 2026

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Where to stay in Eastern South Dakota

Find the best Eastern South Dakota areas and neighborhoods for the activities you enjoy most. Learn more about Eastern South Dakota

Downtown Sioux Falls

1 out of top 10 points of interest in this area

While visiting Downtown Sioux Falls, you might make a stop by sights like Washington Pavilion of Arts and Science and Old Courthouse Museum.

Northwest Sioux Falls

2 out of top 10 points of interest in this area

While visiting Northwest Sioux Falls, you might make a stop by sights like Sanford Pentagon and Sioux Falls Arena.

Sioux Falls Waterfall City Skyline at Blue Hour Night

Mall District

1 out of top 10 points of interest in this area

While visiting Mall District, you might make a stop by sights like Empire Mall and The District.

A bridge with a unique arch design over a calm river, surrounded by greenery and modern buildings.

North Sioux Falls

When in North Sioux Falls, you can plan a visit to Catfish Bay Water Ski Park and Sanford Pentagon, some noteworthy sights in the nearby area.

View of the beautiful Falls Park at Sioux Falls, South Dakota

South Sioux Falls

If you're looking for some top things to see and do in South Sioux Falls and surrounding area, you can visit Empire Mall and The District.

Stay near popular Eastern South Dakota attractions

A frozen waterfall with a brick structure in the background.

Falls Park

9.4/10 (2,165 reviews)

Falls Park is just one of the places to see in Sioux Falls, so why not enjoy the other things to explore during your travels? Attend a sporting event or discover the area's beautiful waterfalls.

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An aerial view of a university campus with multiple buildings, parking lots, and green spaces.

South Dakota State University

9.6/10 (334 reviews)

Enjoy the collegiate vibe when you visit South Dakota State University, during your trip to Brookings. Experience the area's museums and live music.

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A building with multiple domed roofs and a marquee reading "Mitchell."

Corn Palace

8.6/10 (534 reviews)

After visiting Corn Palace, make a plan to see the other sights and activities in Mitchell. While in this family-friendly area, you can savor the top-notch restaurants.

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Denny Sanford Premier Center

8.8/10 (879 reviews)

You can take time to visit Denny Sanford Premier Center during your travels to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Empire Mall

8.6/10 (1,567 reviews)

You can enjoy retail therapy at Empire Mall during your stay in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Sanford Pentagon

8.2/10 (320 reviews)

Catch an event at Sanford Pentagon during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Sioux Falls Convention Center

8.4/10 (298 reviews)

Learn about the events happening at Sioux Falls Convention Center during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Augustana College

8.2/10 (310 reviews)

Take a campus tour or just explore the area of Augustana College, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.

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Eastern South Dakota Hotel Deals

Days Inn by Wyndham Sioux Falls Empire

3401 Gateway Blvd Sioux Falls SD

Fully refundableReserve now, pay when you stay

$67 nightly

$75 total

Sep 16 - Sep 17

Total with taxes and fees

7.8/10 Good! (1,175 reviews)

"This property is not fancy but it’s very well maintained and a good value for the price."

Reviewed on Aug 27, 2026

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

1301 West Russell Sioux Falls SD

Fully refundableReserve now, pay when you stay

$68 nightly

$77 total

Sep 7 - Sep 8

Total with taxes and fees

Highpoint Hotel

1530 W 22nd St Sioux Falls SD

$126 nightly

$140 total

Sep 12 - Sep 13

Total with taxes and fees

9.8/10 Exceptional! (290 reviews)

"This place is a fantastic place to stay, very clean and super nice people."

Reviewed on Aug 29, 2026

See all 978 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.